The TFOS International Workshop on CLD has addressed many areas of interest within the contact lens community as they relate to characterizing the ever-persistent problem of CLD. As noted, this international group of experts provided a framework that future studies and clinical activities can build upon when working in this area. It is critically important that the definition of CLD (as noted above) be applied in trials and studies that address CLD, including validated outcomes, such that there is consistency across research activities. Likewise, prospective natural history studies, which have not been performed to date, will help us better determine the incidence and risk factors for this condition, including factors that may relate to the patient or contact lenses in some way (e.g., material characteristics, designs, care system character- istics, care regimens). Etiologic considerations, including interactions with the ocular surface and tear film, need better models that will allow improved preclinical insight, and ultimately bench to the clinic translation in the development of novel products. Lastly, clinicians must be diligent in working with patients with CLD. It is important that the process of prevention and management of CLD starts early, perhaps even before the onset of symptoms, to improve the long-term prognosis of successful, safe, and comfortable contact lens wear.

Acknowledgments
Disclosure: Each workshop participant’s disclosure data can be found in the Appendix of the Introduction.